12 Days in Italy: Genoa to Naples Adventure Itinerary

Begin your day with a visit to the iconic Genoa Cathedral (Cattedrale di San Lorenzo). This stunning cathedral is known for its black-and-white striped facade and beautiful interior. Afterward, enjoy breakfast at a nearby café.

Spend your afternoon exploring the fascinating exhibits at the Galata Maritime Museum (Galata Museo del Mare). This museum offers an in-depth look at Genoa's maritime history. For lunch, stop by one of the charming trattorias in the area.

In the evening, take a leisurely walk through Piazza de Ferrari, the city's main square. Admire the grand architecture and perhaps catch an outdoor performance if you're lucky. End your day with dinner at another highly-rated restaurant.

Start your morning with a visit to Boccadasse, a picturesque fishing village within Genoa known for its colorful houses and serene atmosphere. Enjoy breakfast at one of the seaside cafés.

In the afternoon, explore more of Genoa's rich history by visiting Doge's Palace (Palazzo Ducale). This historic building now serves as a cultural center with various exhibitions. Have lunch at another local eatery nearby.

Conclude your day with an evening stroll along Corso Italia, Genoa's famous promenade by the sea. It's an ideal place for people-watching and enjoying some gelato from one of the many vendors.

Depart from Genoa early in the morning and head towards Cinque Terre by train or car. Upon arrival, start exploring this beautiful coastal region beginning with Riomaggiore, where you can have breakfast overlooking stunning sea views.

Spend your afternoon hiking between villages or taking boat rides along Cinque Terre’s rugged coastline. Enjoy lunch in Vernazza, known for its charming harbor and delicious seafood dishes.

As evening falls, relax in Monterosso al Mare on one of its sandy beaches or explore its old town filled with shops and restaurants offering local specialties.

Start your day with a visit to the Florence Duomo (Cattedrale di Santa Maria dei Fiori). This iconic cathedral is a masterpiece of Renaissance architecture, and climbing to the top of Brunelleschi's Dome offers breathtaking views of the city. Enjoy breakfast at a nearby café.

In the afternoon, explore the world-renowned Uffizi Galleries (Gallerie degli Uffizi). Home to an extensive collection of Renaissance art, including works by Botticelli, Michelangelo, and Leonardo da Vinci, this museum is a must-visit for art lovers. For lunch, dine at Enoteca Pinchiorri, known for its exquisite Italian cuisine and extensive wine list.

As evening approaches, take a leisurely stroll across the Ponte Vecchio, Florence's oldest bridge lined with jewelry shops. End your day with dinner at another highly-rated restaurant in the area.

Begin your day with a visit to the Accademia Gallery (Galleria dell'Accademia), home to Michelangelo's David. This iconic sculpture is one of the most famous works of art in the world. Afterward, enjoy breakfast at a nearby café.

Spend your afternoon exploring the beautiful Boboli Gardens (Giardino di Boboli). These historic gardens offer stunning views of Florence and are perfect for a relaxing stroll. For lunch, stop by one of the charming trattorias in the area.

In the evening, head to Piazzale Michelangelo for panoramic views of Florence as the sun sets. It's an ideal spot for photography and reflection. Conclude your day with dinner at another local restaurant.

Depart from Florence early in the morning and head towards Siena by train or car. Upon arrival, start your exploration with a visit to Siena Cathedral (Duomo). This stunning Gothic cathedral is known for its intricate facade and beautiful interior. Enjoy breakfast at a nearby café.

Spend your afternoon wandering through Piazza del Campo, Siena's main square famous for its unique shell shape and historic buildings. Don't miss climbing up Mangia Tower (Torre del Mangia) for spectacular views over Siena. For lunch, dine at La Compagnia dei Vinattieri, known for its delicious Tuscan dishes.

As evening falls, explore more of Siena's medieval charm by visiting Siena Civic Museum (Museo Civico di Siena), located within Palazzo Pubblico on Piazza del Campo. End your day with dinner at another highly-rated restaurant.

Start your day with an excursion into Tuscany’s countryside for an exclusive wine tasting experience at an organic Chianti winery (Wine Experience in an Organic Chianti Winery). Enjoy breakfast en route or upon arrival.

After savoring some fine wines and learning about winemaking processes during guided tours through vineyards and cellars; have lunch featuring local specialties paired perfectly with wines produced on-site.

Return to Siena late afternoon/early evening where you can relax before heading out again if desired – perhaps exploring more hidden gems within this enchanting city or simply enjoying dinner at another recommended eatery such as Salefino Vino e Cucina.

Begin your Roman adventure with a visit to the iconic Colosseum. This ancient amphitheater is one of Rome's most famous landmarks and offers a fascinating glimpse into the city's history. Afterward, enjoy breakfast at a nearby café.

In the afternoon, explore the Roman Forum (Foro Romano), which was the center of political and social life in ancient Rome. Wander through the ruins and imagine what life was like during the height of the Roman Empire. For lunch, dine at a highly-rated restaurant in the area.

As evening approaches, make your way to Trevi Fountain (Fontana di Trevi). Toss a coin into the fountain to ensure your return to Rome. End your day with dinner at another local restaurant.

Vatican Museums (Musei Vaticani) should be your first stop today. These museums house an incredible collection of art and historical artifacts, including Michelangelo's Sistine Chapel ceiling. Enjoy breakfast at a nearby café before heading inside.

St. Peter's Basilica (Basilica di San Pietro) is next on your list. This magnificent church is one of the largest in the world and offers stunning views from its dome. For lunch, try one of the charming trattorias near Vatican City.

Piazza Navona is perfect for an evening stroll. This lively square is known for its beautiful fountains and vibrant atmosphere. Conclude your day with dinner at another highly-rated restaurant.

Naples National Archaeological Museum (Museo Archeologico Nazionale) should be your first stop today. This museum houses one of Italy's most important collections of Greek and Roman antiquities. Enjoy breakfast at a nearby café before exploring.

Spaccanapoli, Naples' historic center, is perfect for an afternoon walk. Wander through narrow streets filled with shops, cafes, and historic buildings. For lunch, dine at Pizzeria Sorbillo, famous for its delicious Neapolitan pizza.

Piazza del Plebiscito is ideal for an evening visit. This grand square is surrounded by impressive buildings and offers a great place to relax as you watch local life unfold around you. End your day with dinner at another recommended eatery such as Ristorante Palazzo Petrucci.