16 Days in Rome, Seville, Madrid, and Barcelona Itinerary

Begin your day with a visit to Vatican City. Join the Rome: Vatican Museum and Sistine Chapel Official Guided Tour for an unforgettable experience exploring some of the world's most famous art collections. Marvel at Michelangelo's masterpiece on the ceiling of the Sistine Chapel and wander through St. Peter's Basilica.

After your Vatican tour, cross over to Trastevere for lunch at Tonnarello, a popular spot known for its authentic Italian pasta dishes. Spend your afternoon wandering through Trastevere's charming streets filled with colorful buildings, artisan shops, and quaint cafes.

In the evening, visit Campo de' Fiori for its lively market atmosphere by day and vibrant nightlife after dark. Enjoy dinner at Hostaria Farnese, which offers a delightful menu featuring local specialties.

Start your day with a visit to Capitoline Hill (Campidoglio e Musei Capitolini). Explore its museums filled with classical sculptures and Renaissance art while enjoying stunning views over Rome from this historic hilltop location.

For lunch, head to Pane e Salame near Trevi Fountain (Fontana di Trevi). Afterward, make your way towards Trevi Fountain itself – one of Rome’s most famous landmarks – where you can toss coins into its waters as per tradition before continuing on foot towards Pantheon (Pantheon), another iconic site steeped in history.

Conclude your third day by visiting Piazza di Spagna (Spanish Steps) during sunset when it becomes even more picturesque under soft evening light; then dine at Alla Rampa, offering delicious Italian cuisine right next door.

Start your day with a visit to the Royal Alcázar of Seville (Real Alcázar de Sevilla). This stunning palace complex, known for its intricate Moorish architecture and lush gardens, is a must-see. Join the Seville: Alcázar Guided Palace Tour with Priority Access to skip the lines and gain insightful knowledge about the history and significance of this UNESCO World Heritage site.

After exploring the Alcázar, head to El Rinconcillo for a traditional Andalusian lunch. This historic tavern is famous for its tapas and local dishes. Post-lunch, take a leisurely stroll through Maria Luisa Park (Parque de María Luisa), where you can relax amidst beautiful landscapes and fountains.

In the evening, visit Plaza de España (Plaza de España), an architectural marvel that showcases Spain's regional styles. The plaza is especially enchanting at sunset. For dinner, dine at Vega 10, known for its innovative Spanish cuisine in a cozy setting.

Seville Cathedral (Catedral de Santa María de la Sede) is your first stop today. This Gothic masterpiece is one of the largest cathedrals in the world and houses Christopher Columbus' tomb. Join the Seville: Cathedral, Giralda, and Royal Alcázar Guided Tour to get an in-depth understanding of its history and architecture.

La Azotea is perfect for lunch with its modern take on traditional Spanish dishes. Afterward, explore Barrio Santa Cruz (Barrio Santa Cruz), Seville's old Jewish quarter filled with narrow streets, whitewashed houses, and charming squares.

Los Gallos Tablao Flamenco offers an authentic flamenco experience in an intimate setting. Enjoy dinner at Taberna del Alabardero, which serves exquisite Andalusian cuisine in a historic mansion.

Prado Museum (Museo del Prado) should be your first stop in Madrid. This world-renowned museum houses masterpieces by artists like Velázquez, Goya, and El Greco. Opt for the Madrid: Prado Museum Guided Tour and Entry Ticket to make the most of your visit.

Sobrino de Botín, known as the oldest restaurant in the world according to Guinness World Records, offers a delightful lunch experience with traditional Spanish fare. Post-lunch, head to Retiro Park (Parque de El Retiro) for a relaxing afternoon amidst beautiful gardens and sculptures.

In the evening, explore Gran Vía (Gran Vía), Madrid’s bustling shopping street lined with theaters and restaurants. Enjoy dinner at Casa Lucio, famous for its classic Spanish dishes like huevos rotos.

Begin your day with a visit to the Royal Palace of Madrid (Palacio Real de Madrid). This opulent palace is the official residence of the Spanish Royal Family, although it is now only used for state ceremonies. Opt for the Madrid: Royal Palace Tour with Optional Royal Collections to explore its lavish rooms and learn about its history.

For lunch, head to La Vaca y La Huerta, known for its farm-to-table dishes. Afterward, visit the nearby Almudena Cathedral (Catedral de la Almudena), which stands in stark contrast to the Royal Palace with its neo-Gothic architecture. Spend your afternoon wandering through Plaza Mayor (Plaza Mayor), a grand square surrounded by historic buildings and bustling cafes.

In the evening, experience Madrid's vibrant nightlife at Puerta del Sol (Puerta del Sol). This central square is a hub of activity and a great place to people-watch. Enjoy dinner at Casa Labra, famous for its tapas and traditional Spanish cuisine.

Start your Barcelona adventure with a visit to the iconic Sagrada Familia (Sagrada Familia). This masterpiece by Antoni Gaudí is still under construction but remains one of the most visited landmarks in Spain. Join the Barcelona: Sagrada Familia Entry Ticket with Audio Guide for an informative tour of this breathtaking basilica.

For lunch, dine at Cervecería Catalana, known for its delicious tapas. Afterward, head to Park Güell (Park Güell), another Gaudí creation that offers whimsical architecture and stunning views over Barcelona. Opt for the Barcelona: Park Güell Guided Tour with Fast-Track Ticket to make your visit seamless.

In the evening, explore Passeig de Gracia (Passeig de Gracia), where you can admire more of Gaudí's works like Casa Batlló (Casa Batlló) and Milà House (Casa Milà). Enjoy dinner at El Nacional, a unique dining space offering various Spanish cuisines under one roof.

Begin your day with a visit to Ciutat Vella (Ciutat Vella), Barcelona’s Old Town filled with narrow streets, historic buildings, and vibrant markets. Join the Barcelona: Old Town and Gothic Quarter Walking Tour to delve into its rich history and hidden gems.

Have lunch at Bar Lobo, known for its Mediterranean dishes in a relaxed setting. Post-lunch, explore Las Ramblas (Las Ramblas), Barcelona’s famous tree-lined street bustling with shops, cafes, and street performers.

Conclude your day by visiting El Born (El Born), a trendy neighborhood known for its artistic vibe and lively nightlife. Dine at Cal Pep, renowned for its seafood tapas.

Start your day with a visit to Barceloneta Beach (Barceloneta Beach). This popular beach is perfect for a morning stroll or even a quick dip in the Mediterranean Sea. After enjoying the beach, head over to the nearby Barcelona: Coastline Boat Trip with Snacks and Cava for a relaxing boat tour along Barcelona's stunning coastline.

For lunch, dine at La Cova Fumada, known for its traditional Catalan dishes and fresh seafood. Afterward, explore Montjuic Park (Parc de Montjuïc), where you can visit attractions like the Magic Fountain (Font Màgica) and Montjuïc Castle (Castell de Montjuïc). The park offers beautiful gardens, museums, and panoramic views of the city.

In the evening, head to El Born (El Born) for its vibrant nightlife. Enjoy dinner at El Xampanyet, a popular spot known for its tapas and cava. After dinner, consider attending the Barcelona: Flamenco Show at Tablao Flamenco Cordobes for an authentic Spanish flamenco experience.

Reina Sofia Museum (Museo Nacional Centro de Arte Reina Sofia) is your first stop today. This museum houses an impressive collection of contemporary art, including works by Picasso and Dalí. Opt for the Madrid: Reina Sofía Museum Entrance Ticket to explore its vast galleries.

Botín is perfect for lunch with its historic charm and delicious Spanish cuisine. Afterward, visit Plaza de Cibeles (Plaza de Cibeles), one of Madrid’s most iconic squares featuring stunning architecture like Cybele Palace (Palacio de Cibeles). Spend your afternoon exploring Retiro Park (Parque de El Retiro), where you can rent a rowboat on the lake or simply relax in its beautiful gardens.

Madrid: Flamenco Show at Tablao Las Carboneras offers an unforgettable evening of traditional Spanish music and dance. Enjoy dinner at Casa Lucio, famous for its classic Spanish dishes like huevos rotos.

Seville Aquarium Admission Ticket should be your first stop today. This family-friendly attraction offers fascinating marine exhibits that are sure to delight both adults and toddlers alike.

La Brunilda Tapas is ideal for lunch with its creative tapas menu. Afterward, take a leisurely stroll through Maria Luisa Park (Parque de María Luisa), where you can enjoy beautiful landscapes, fountains, and even rent a rowboat on Plaza de España’s canal.

Conclude your day with an authentic flamenco experience at Seville: Casa de la Memoria Flamenco Show. For dinner, dine at Vega 10, known for its innovative Spanish cuisine in a cozy setting.

Begin your day with a visit to the Gaudí House Museum (Casa Museu Gaudí). This museum, located in Park Güell, offers an intimate look into the life and works of Antoni Gaudí. After exploring the museum, join the Barcelona: Guided Gaudi Tour to Sagrada, Houses & Park Guell for a comprehensive tour of Gaudí's masterpieces, including Casa Batlló and Casa Milà.

For lunch, head to Teresa Carles, known for its delicious vegetarian dishes. Afterward, explore the Gothic Quarter (Barri Gotic), where you can wander through narrow medieval streets filled with history and charm. Don't miss visiting the Barcelona Cathedral (Catedral de Barcelona) and Placa del Rei (Placa del Rei).

In the evening, take a leisurely stroll along Las Ramblas (Las Ramblas), Barcelona’s famous tree-lined street bustling with shops, cafes, and street performers. Enjoy dinner at Can Culleretes, one of Barcelona's oldest restaurants known for its traditional Catalan cuisine.

Retiro Park (Parque de El Retiro) is your first stop today. This expansive park offers beautiful gardens, sculptures, and even a lake where you can rent rowboats. Spend your morning exploring its many attractions.

La Barraca is perfect for lunch with its delicious paella dishes. Afterward, visit the Thyssen-Bornemisza Museum (Museo Nacional Thyssen-Bornemisza), which houses an impressive collection of European art from various periods.

Madrid: Flamenco Show at Tablao Sala Temple with Drink offers an unforgettable evening of traditional Spanish music and dance. Enjoy dinner at El Club Allard, known for its innovative Spanish cuisine in an elegant setting.

Seville: Alcázar Guided Palace Tour with Priority Access should be your first stop today. This stunning palace complex is known for its intricate Moorish architecture and lush gardens.

Eslava is ideal for lunch with its creative tapas menu. Afterward, explore Triana Bridge (Puente de Isabel II) and the surrounding El Arenal District (El Arenal District), known for their vibrant atmosphere and historic significance.

Conclude your day with an authentic flamenco experience at Seville: Live Flamenco Show Ticket at the Theater. For dinner, dine at Abantal, a Michelin-starred restaurant offering exquisite Andalusian cuisine.

Start your final day in Barcelona with a visit to the vibrant La Boqueria Market (Mercat de la Boqueria). This bustling market is a feast for the senses, offering a wide array of fresh produce, seafood, meats, and local delicacies. Stroll through the colorful stalls and perhaps pick up some last-minute souvenirs or snacks for your journey.

For lunch, head to El Quim de la Boqueria, located within the market itself. This popular eatery is known for its delicious tapas and fresh ingredients sourced directly from the market. After lunch, take a leisurely walk to Ciutadella Park (Parc de la Ciutadella), one of Barcelona's most beautiful green spaces. Enjoy a relaxing afternoon amidst its lush gardens, fountains, and even take a boat ride on the park's lake.

In the evening, make your way to Montjuïc Mountain (Montjuïc Mountain) for stunning panoramic views of Barcelona. Visit Montjuïc Castle (Castell de Montjuïc) and explore its historic grounds. As the sun sets, head to Tickets, an innovative tapas bar by renowned chef Albert Adrià, for a memorable farewell dinner. Conclude your trip with a visit to the Magic Fountain (Font Màgica) for its spectacular light and music show.