Ultimate 2-Week Italy Itinerary with Rome Highlights Itinerary

Kick off your day with a hearty breakfast at La Pergola, one of Rome's most prestigious restaurants. After breakfast, head to the Vatican Museums (Musei Vaticani) with your Vatican Museums & Sistine Chapel Entrance Ticket. Explore the vast collection of art and artifacts, culminating in the breathtaking Sistine Chapel (Cappella Sistina).

For lunch, indulge in the innovative pizzas at Pizzarium, a true gem for pizza lovers. Post-lunch, visit the spiritual oasis of St. Peter's Basilica (Basilica di San Pietro) and marvel at its grandeur. Climb to the top of the dome for a panoramic view of the Vatican City.

Enjoy a relaxed evening in the charming Trastevere district. Dine at Trattoria Da Cesare al Casaletto, known for its Roman specialties. After dinner, take a stroll through the cobblestone streets and soak in the bohemian atmosphere.

Start your day with a delightful breakfast at Caffè Sant'Eustachio, famous for its coffee. Then, visit the lush Borghese Gallery (Galleria Borghese) and enjoy the masterpieces of art and the serene Borghese Gardens (Villa Borghese).

For lunch, head to Antico Arco and savor the contemporary Roman cuisine in a cozy setting. Post-lunch, take a guided tour of the Catacombs of Rome (Catacombe di Roma) to explore the ancient underground burial chambers and learn about early Christian history.

As the day winds down, visit the majestic Pantheon and witness the architectural marvel. Nearby, enjoy a sophisticated dining experience at Il Pagliaccio, which offers a blend of innovation and tradition in its dishes. Conclude your evening with a leisurely walk through the historic center, admiring the beautiful piazzas and fountains.

Explore the lesser-known sites of Rome, starting with the Arch of Constantine (Arco di Costantino) and the nearby Circus Maximus (Circo Massimo). Enjoy a casual breakfast at Antico Forno Roscioli, known for its freshly baked goods.

For lunch, visit Trapizzino Testaccio and indulge in the innovative "trapizzino," a cross between a pizza and a sandwich, filled with delicious Roman-style fillings. Afterward, take a self-guided tour of the Rome Colosseum & Roman Forum Skip-the-Line Entry Ticket and explore these iconic landmarks at your own pace.

Experience the vibrant atmosphere of the Rome Civitavecchia Cruise Port (Civitavecchia Terminal Crociere) and enjoy a delightful seafood dinner at La Gensola, known for its fresh catch of the day. Savor the flavors of the Mediterranean cuisine and reminisce about the day's adventures.

Embark on an early morning journey to the ancient city of Pompeii with your From Rome Pompeii, Amalfi Coast and Positano Day Trip. Explore the remarkably preserved ruins and learn about the history of this once-thriving Roman city.

After immersing yourself in the ancient world, continue to the breathtaking Amalfi Coast. Enjoy a leisurely lunch with a view at Ristorante Marina Grande in Positano, and take in the stunning coastal scenery.

As the sun sets, explore the charming town of Amalfi, known for its historic cathedral and vibrant streets. Enjoy a delightful dinner at Ristorante Parsifal, offering a menu inspired by the flavors of the Mediterranean. Relax and reflect on the day's adventures before heading back to Rome.

Catch an early train to the beautiful city of Florence, the heart of Tuscany. Upon arrival, enjoy a classic Florentine breakfast at La Ménagère, a unique concept that combines a café, restaurant, and flower shop in a stunning setting.

Spend your afternoon exploring the cultural treasures of Florence, including the iconic Duomo and the Uffizi Gallery (Galleria degli Uffizi). For lunch, indulge in the gourmet sandwiches at I Due Fratellini, a local favorite for a quick and delicious meal.

As the day winds down, take a leisurely stroll across the Ponte Vecchio, the famous bridge lined with shops. Enjoy a sumptuous dinner at Trattoria Sostanza, known for its traditional Tuscan dishes and warm hospitality. After dinner, catch a train back to Rome and reminisce about your day in Florence.

Start your day with a visit to the Spanish Steps (Piazza di Spagna) and the upscale shopping street, Via Condotti. Enjoy a luxurious breakfast at Antico Caffè Greco, the oldest bar in Rome, known for its opulent décor and rich history.

For lunch, head to Il Gabriello and indulge in the traditional Roman dishes served in a cozy, rustic setting. Post-lunch, take a guided tour of the Rome St. Peter's Basilica, Dome Climb & Papal Tombs Tour and gain insights into the history and art of this magnificent basilica.

Explore the vibrant Campo de' Fiori market and the nearby Jewish Ghetto (Ghetto Ebraico), and learn about the rich Jewish heritage of Rome. Enjoy a sophisticated dinner at Imàgo, located on the panoramic rooftop of the Hassler Hotel, offering stunning views of the city along with innovative Mediterranean cuisine.

Enjoy a relaxed morning with breakfast at Coromandel, a quaint café known for its pastries and coffee. Then, take a self-guided tour of the Rome Pantheon Skip-the-Line Entry Ticket and Audio Guide and marvel at the architectural marvel of the Pantheon.

For lunch, visit Mercato Centrale Roma and explore the diverse food stalls offering a wide range of Italian and international cuisines. Post-lunch, take a leisurely walk to the Monti district, known for its bohemian vibe and eclectic boutiques.

Dine at Settembrini for a contemporary Italian dining experience in an elegant setting. After dinner, take in the views of the city from the Monte Pincio (Pincian Hill) and enjoy a leisurely stroll through the lush gardens, reflecting on the beauty of Rome.

Begin your day with a visit to the Ara Pacis, an ancient altar dedicated to peace. Enjoy a delightful breakfast at Casa Bleve, a historic wine bar that also serves a selection of gourmet dishes.

For lunch, head to Il Convivio Troiani and indulge in the Michelin-starred cuisine in an elegant setting. Post-lunch, visit the Centrale Montemartini, a unique museum housed in a former power plant, showcasing a juxtaposition of classical sculpture and industrial machinery.

Dine at Ad Hoc for a contemporary take on traditional Roman dishes. After dinner, take a guided tour of the Rome St. Peter's Basilica Tour with Dome and Papal Tombs and explore areas of the basilica not usually accessible to the public, including the papal tombs and the stunning dome.

Enjoy a peaceful morning with breakfast at Cecco, a charming café nestled in the Trastevere district. Then, visit the Villa Farnesina, a hidden gem with exquisite frescoes and a serene garden, allowing you to escape the hustle and bustle of the city.

For lunch, head to Il Sanlorenzo, a renowned seafood restaurant that prides itself on serving the freshest catch. Post-lunch, take a guided tour of the Rome Vatican Museums, Sistine Chapel, and Basilica Tour and immerse yourself in the art and history of the Vatican.

Dine at Il Pagliaccio, a two-Michelin-starred restaurant known for its innovative and artistic approach to Italian cuisine. After dinner, take a moonlit stroll to the Piazza Navona and admire the beautiful Baroque fountains and architecture.

Start your day with a visit to the Mercati di Traiano - Museo dei Fori Imperiali, a museum that showcases the history of the Imperial Forums. Enjoy a delightful breakfast at Antico Caffè della Pace, a historic café known for its elegant ambiance and excellent coffee.

For lunch, head to Pane e Salame and indulge in a selection of artisanal sandwiches and charcuterie. Post-lunch, take a guided tour of the Rome Colosseum, Roman Forum & Palatine Hill Priority Ticket and explore the iconic landmarks with the insights of an expert guide.

Dine at Trattoria Monti for a taste of traditional Roman cuisine in a cozy, family-run trattoria. After dinner, take a guided tour of the Rome Colosseum Underground and Ancient Rome Tour and gain access to the underground chambers and the arena floor, experiencing the Colosseum in a unique way.

Begin your day with a visit to the Galleria Doria Pamphilj, a private art collection housed in a stunning palace. Enjoy a sumptuous breakfast at Emma Pizzeria, known for serving some of the best pizzas in Rome.

For lunch, head to La Gatta Mangiona and indulge in their creative pizzas and other mouthwatering dishes. Post-lunch, take a guided tour of the Rome Vatican Museums, Sistine Chapel & Basilica Entry and explore the rich collections of the Vatican.

Dine at Monti for a contemporary dining experience in the heart of Rome's Monti district. After dinner, take a leisurely walk to the Mercato di Testaccio and explore the vibrant market, sampling local delicacies and soaking in the lively atmosphere.

Start your day with a visit to the Museo Nazionale di Castel Sant'Angelo (Mausoleo di Adriano), a museum housed in a historic mausoleum. Enjoy a delightful breakfast at Antico Forno La Renella, a bakery that has been serving traditional Roman breads and pastries for generations.

For lunch, head to La Pergola, Rome's only three-Michelin-starred restaurant, and indulge in an unforgettable dining experience. Post-lunch, take a guided tour of the Rome Shuttle Bus Transfer to or from Fiumicino Airport and enjoy a hassle-free transfer to the airport, reflecting on the memories of your time in Rome.

As you bid farewell to Rome, take a moment to enjoy the city's skyline from the Gianicolo (Janiculum), a panoramic terrace offering stunning views. End your Roman journey with a visit to St. Peter's Square (Piazza San Pietro) and the St. Peter's Basilica (Basilica di San Pietro), taking in the grandeur of the Vatican before heading to your next destination.