21-Day South American Road Trip Adventure Itinerary

Start your day with a visit to La Recoleta Cemetery Guided Tour in English. This famous cemetery is known for its elaborate mausoleums and is the final resting place of many notable Argentinians including Eva Perón. The guided tour will provide fascinating insights into Argentina's history and culture. Enjoy breakfast at nearby café La Biela, which offers great coffee and pastries.

In the afternoon, explore more cultural landmarks with Buenos Aires Private Tango Lesson. Learn about this passionate dance from professional instructors who will guide you through basic steps and techniques. It's not only fun but also gives you deeper appreciation for this integral part of Argentine culture. For lunch afterward head over to Sarkis, known for its delicious Middle Eastern cuisine.

Conclude your third day by visiting Palermo Soho for some shopping or simply soaking up its lively atmosphere before heading out for dinner at another top-rated restaurant: Don Julio which is famous among locals as well as tourists alike due their high-quality steaks paired perfectly wines making it ideal spot wrap up eventful yet enriching days spent exploring vibrant capital city.

Begin your day with an early flight from Buenos Aires to Iguazu Falls. Upon arrival, head straight to Iguazu Falls, one of the most breathtaking natural wonders in the world. Spend your morning exploring the various trails and viewpoints that offer stunning views of these magnificent waterfalls. Don't forget to bring your camera! For breakfast before your flight, grab a quick bite at Pani near your hotel.

After marveling at Iguazu Falls all morning, take part in Buenos Aires Iguazu Falls Semi-Private Tour with Flights. This tour includes a boat ride that takes you up close to the falls for an exhilarating experience you won't soon forget. For lunch, enjoy a meal at La Selva, located within Iguazu National Park.

Return to Buenos Aires in the evening and unwind after a day full of adventure. Consider visiting Buenos Aires Rooftop Barbecue & Argentinean Flavors.#1 Rank for dinner where you can savor delicious Argentine barbecue while enjoying panoramic views of the city skyline.

Start your day with a scenic drive from Buenos Aires to Montevideo, Uruguay. This journey will take approximately 3 hours by ferry and then another 2 hours by car. Upon arrival, check into your hotel and freshen up. Begin your exploration with a visit to Montevideo Metropolitan Cathedral (Catedral de Montevideo). This historic cathedral is a beautiful example of colonial architecture and offers a peaceful respite in the heart of the city. For breakfast, stop by Café Brasilero, one of the oldest cafes in Montevideo.

In the afternoon, delve into Montevideo's rich history with Montevideo Private custom tour with a local guide. This personalized tour will take you to some of the city's most iconic landmarks, including Plaza Independencia, Teatro Solis, and Mercado del Puerto. You'll gain insights into the city's culture and history from your knowledgeable guide. For lunch, enjoy traditional Uruguayan cuisine at La Pulpería, known for its delicious parrillada (barbecue).

As evening approaches, head to the Rambla of Montevideo (Rambla de Montevideo) for a leisurely stroll along the waterfront. The Rambla is a popular spot for locals and visitors alike to enjoy beautiful views of the Rio de la Plata. End your day with dinner at Es Mercat, a highly-rated seafood restaurant that offers fresh catches of the day prepared in various styles.

Begin your day with an early drive from Montevideo to Punta del Este, which takes about 2 hours. Upon arrival, head straight to Hand of Punta del Este (La Mano de Punta del Este), an iconic sculpture that has become a symbol of this beach resort town. Spend some time taking photos and enjoying the beautiful beach scenery. For breakfast on-the-go, grab some pastries and coffee from Medialunas Calentitas before hitting the road.

In the afternoon, explore more of Punta del Este with From Montevideo Punta del Este Full-Day Tour. This comprehensive tour will take you to some of the town's most famous attractions including Casapueblo (Museo Taller de Casapueblo), Port of Punta del Este (Puerto de Punta del Este), and Gorlero Avenue (Avenida Gorlero). For lunch during your tour stop at Isidora, which offers great views along with delicious seafood dishes.

Conclude your day in Punta del Este by visiting Playa Brava or Playa Mansa for sunset views before heading out for dinner at another top-rated restaurant: Lo de Tere. Known for its gourmet cuisine featuring local ingredients paired perfectly wines making it ideal spot wrap up eventful yet enriching days spent exploring vibrant coastal city.

Start early morning drive from Punta Del Este towards Colonia Del Sacramento taking approximately 3 hours via Route 1 Westbound direction passing through picturesque countryside landscapes arriving around mid-morning ready explore UNESCO World Heritage Site starting off visiting Gateway Citadel Puerta Ciudadela impressive stone gate marking entrance old town dating back colonial times offering glimpse past historical significance region complemented breakfast nearby cafe R-Lentas Maravillas offering delightful assortment pastries coffees set tone perfect start exploring further.

Continue immersing yourself rich history culture guided walking tour A-From Montevideo Colonia Day Trip Sightseeing covering key landmarks such as Calle Los Suspiros Street Sighs Basilica Holy Sacrament among others learning fascinating stories behind each site while enjoying scenic beauty cobblestone streets lined colorful buildings flowers blooming everywhere creating picturesque setting ideal capturing memories lunch R-El Drugstore renowned eclectic menu featuring fusion flavors catering diverse palates ensuring satisfying meal amidst charming ambiance unique establishment.

As sun sets over Rio Plata take leisurely stroll along coastal promenade soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit historic town finally heading dinner R-La Florida celebrated traditional Uruguayan dishes served warm inviting environment perfect ending enriching culturally immersive day spent discovering hidden gems quaint colonial gem nestled shores majestic river.

Start your day with a visit to Santo Domingo Savio Library (Biblioteca de España). This modern architectural marvel is not only a library but also a cultural center that offers stunning views of the city. The library is located in one of Medellín's most transformed neighborhoods, making it a symbol of the city's social and urban renewal. For breakfast, head to Café Revolución, known for its excellent coffee and pastries.

In the afternoon, explore more of Medellín with Bogotá Private City Tour of Monserrate, Gold, and Botero. This tour will take you to some of the city's most iconic landmarks, including Plaza Botero, where you can see the famous sculptures by Fernando Botero. You'll also visit the Museum of Antioquia to learn more about the region's history and culture. For lunch, enjoy a meal at El Cielo, a highly-rated restaurant known for its innovative Colombian cuisine.

As evening falls, take a ride on Medellín's famous Metrocable to get panoramic views of the city as it lights up at night. Conclude your day with dinner at Carmen, one of Medellín's top restaurants offering a fusion of Colombian and international flavors in an elegant setting.

Cartagena Cathedral (St. Catherine of Alexandria Cathedral) is your first stop today. This historic cathedral is one of Cartagena's most important religious sites and offers beautiful architecture and serene ambiance. After exploring the cathedral, enjoy breakfast at Época Espresso Bar, which serves delicious coffee and breakfast options.

Palace of Inquisition (Palacio de la Inquisicion) awaits you in the afternoon. This museum provides fascinating insights into Cartagena's colonial past and the Spanish Inquisition's impact on the region. Wander through its exhibits and learn about this dark chapter in history while admiring the building's colonial architecture. For lunch, dine at La Cevichería, famous for its fresh seafood dishes.

Plaza de San Diego is perfect for an evening stroll. This lively square is surrounded by colorful colonial buildings and offers a variety of dining options and street performances. End your day with dinner at Donjuán, known for its contemporary Caribbean cuisine that blends traditional flavors with modern techniques.

La Chorrera Waterfall will be your adventure destination today. Start early with a drive from Bogotá to this stunning natural wonder located just outside the city. The hike to La Chorrera takes you through lush forests and offers breathtaking views along the way. Make sure to pack some snacks or grab breakfast at Masa before heading out.

Bogotá Guided 5-Hour Coffee Farm Tour will provide you with an immersive experience into Colombia's coffee culture. Visit a local coffee farm where you'll learn about coffee production from bean to cup while enjoying beautiful countryside scenery. For lunch during your tour stop by Andrés Carne de Res, which offers traditional Colombian dishes in a vibrant setting.

Return back Bogotá evening unwind after full adventurous day perhaps visiting local bar lounge such as R-Gaira Café Cumbia House renowned live music performances great cocktails creating perfect atmosphere relax reflect upon day's experiences.

Begin your day with a visit to Bogotá Museum of Modern Art (MAMBO). This museum is home to an impressive collection of contemporary Colombian art and offers a fascinating insight into the country's modern artistic movements. After exploring the museum, enjoy breakfast at Azahar Coffee, known for its excellent coffee and delicious pastries.

In the afternoon, delve deeper into Bogotá's rich history with Bogotá Private Graffiti Tour in La Candelaria. This tour will take you through the vibrant streets of La Candelaria, where you'll see some of the city's most impressive street art and learn about the stories behind these colorful murals. For lunch, head to La Puerta Falsa, a historic eatery famous for its traditional Colombian dishes.

Bogotá Craft Beer Tour with Tasting is perfect for winding down your day. Explore Bogotá's burgeoning craft beer scene with visits to several local breweries where you can sample a variety of unique brews. End your evening with dinner at Casa Vieja, which offers a cozy atmosphere and serves hearty Colombian cuisine.

Villa de Leyva Trip by Private Transportation starts early today. Depart from Bogotá and enjoy a scenic drive to this charming colonial town nestled in the Andes Mountains. Upon arrival, begin your exploration with a visit to Plaza Mayor, one of the largest town squares in South America. For breakfast on-the-go, grab some pastries from Panadería La Villa before hitting the road.

Quinta de Bolívar Museum awaits you in the afternoon. This historic house museum was once home to Simón Bolívar and offers fascinating insights into his life and legacy. Wander through its beautifully preserved rooms and gardens while learning about Colombia's fight for independence. For lunch, dine at El Rincón Gourmet De la Villa, known for its delicious regional cuisine.

La Catedral Primada is perfect for an evening visit as you return back to Bogotá after spending enriching day exploring historical wonders Villa Leyva finally heading dinner R-Harry Sasson renowned restaurant offering fusion flavors modern techniques creating memorable dining experience wrapping up culturally immersive day.

Natural Pool will be your adventure destination today as you embark on an early morning drive from Bogotá to San Gil taking approximately five hours passing through picturesque countryside landscapes arriving around mid-morning ready explore natural beauty region starting off visiting Natural Pool refreshing swim amidst serene surroundings complemented breakfast nearby cafe R-Gringo Mike's offering delightful assortment pastries coffees set tone perfect start adventurous day.

From Bogota Hike to Colombia's Highest Waterfall provides thrilling experience hiking through lush forests reaching breathtaking heights witnessing majestic waterfall cascading down cliffs creating awe-inspiring sight capturing memories lunch during hike enjoying packed meal prepared beforehand ensuring energy levels maintained throughout journey making most out outdoor adventure.

As sun sets over scenic landscapes San Gil take leisurely stroll along riverside soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit adventurous town finally heading dinner R-Macondo celebrated traditional Colombian dishes served warm inviting environment perfect ending enriching physically engaging day spent discovering hidden gems nestled heart nature.

Start your day with a visit to San Salvador de Jujuy. This charming city is known for its rich history and vibrant culture. Begin your exploration at the Plaza Belgrano, the city's main square, where you can admire the beautiful colonial architecture and visit the Cathedral of San Salvador de Jujuy. For breakfast, head to Café del Tiempo, a popular spot known for its excellent coffee and pastries.

In the afternoon, delve deeper into the local culture with a visit to the Museo Histórico Provincial. This museum offers fascinating exhibits on the region's history and indigenous cultures. Afterward, take a leisurely stroll through Parque San Martín, a beautiful park that offers a peaceful respite from the bustling city. For lunch, enjoy traditional Argentine cuisine at El Bodegón, a highly-rated restaurant known for its delicious empanadas.

As evening falls, experience the vibrant nightlife of San Salvador de Jujuy with a visit to one of its many bars or lounges. Consider visiting La Estación, a popular spot that offers live music and a wide selection of drinks. End your day with dinner at Restaurante Viracocha, which serves gourmet Argentine dishes in an elegant setting.

Begin your day with an early drive from San Salvador de Jujuy to Cerro Chapelco, which takes approximately 4 hours. Upon arrival, head straight to Cerro Chapelco Ski Resort, one of Argentina's premier ski destinations. Spend your morning hitting the slopes and enjoying the breathtaking mountain scenery. For breakfast before your drive, grab some pastries and coffee from Panadería La Nueva in San Salvador de Jujuy.

In the afternoon, continue your adventure at Cerro Chapelco with activities such as snowboarding or taking a scenic chairlift ride to enjoy panoramic views of the surrounding Andes Mountains. For lunch, dine at La Costa del Pueblo, located within the resort and offering hearty meals perfect for refueling after an active morning.

As evening approaches unwind après-ski style by visiting cozy lodge bar enjoying warm beverages while reflecting upon day's adventures finally heading dinner R-El Regional renowned restaurant serving traditional Patagonian dishes creating perfect ending eventful yet exhilarating day spent exploring majestic slopes picturesque mountain resort.

Start your day with an early flight from Cerro Chapelco to Ushuaia, often referred to as 'The End of The World'. Upon arrival head straight explore A-Martial Glacier breathtaking natural wonder offering stunning views over Beagle Channel surrounding landscapes making ideal spot capturing memorable photographs complemented breakfast nearby cafe R-Kaupe offering delightful assortment pastries coffees set tone perfect start adventurous day.

In afternoon delve deeper into local history culture visiting A-Magallanes Regional Museum Braun-Menendez Palace beautifully preserved mansion showcasing artifacts exhibits detailing rich heritage region providing fascinating insights life early settlers explorers lunch enjoy meal R-Ramos Generales highly-rated restaurant known delicious seafood dishes served amidst charming rustic ambiance enhancing overall dining experience further immersing oneself unique atmosphere southernmost city world.

As sun sets over dramatic landscapes Ushuaia take leisurely stroll along waterfront soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit historic town finally heading dinner R-Kuar celebrated traditional Argentine dishes served warm inviting environment perfect ending enriching culturally immersive day spent discovering hidden gems nestled shores majestic Beagle Channel.

Begin your day with an early drive from Ushuaia to El Calafate, which takes approximately 8 hours. Upon arrival, head straight to Estancia Cristina, a historic ranch located in the heart of Patagonia. Spend your morning exploring the ranch and learning about its history and the traditional Patagonian way of life. For breakfast before your drive, grab some pastries and coffee from Café Bar Banana in Ushuaia.

In the afternoon, embark on a guided tour of the surrounding area, including a visit to the Upsala Glacier. This tour offers breathtaking views of one of the largest glaciers in South America and provides fascinating insights into the region's geology and natural history. For lunch, enjoy a meal at La Tablita, a highly-rated restaurant known for its delicious Argentine barbecue.

As evening approaches unwind back El Calafate visiting cozy lodge bar enjoying warm beverages while reflecting upon day's adventures finally heading dinner R-Mi Rancho renowned restaurant serving traditional Patagonian dishes creating perfect ending eventful yet exhilarating day spent exploring majestic landscapes picturesque Patagonian region.

Start your day with a visit to Perito Moreno Glacier, one of Argentina's most famous natural attractions. This massive glacier is located within Los Glaciares National Park and offers stunning views from various walkways and viewing platforms. Spend your morning exploring the glacier and taking in its awe-inspiring beauty. For breakfast before heading out grab some pastries coffee R-Viva La Pepa Creppes & Passion setting tone perfect start adventurous day.

In afternoon continue adventure embarking guided ice trekking tour Perito Moreno providing unique opportunity walk across surface glacier while learning about its formation dynamics guides ensuring safe enjoyable experience lunch during tour enjoying packed meal prepared beforehand ensuring energy levels maintained throughout journey making most out outdoor adventure amidst breathtaking surroundings.

As sun sets over dramatic landscapes El Calafate take leisurely stroll along waterfront soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit iconic natural wonder finally heading dinner R-Isabel Cocina al Disco celebrated traditional Argentine dishes served warm inviting environment perfect ending enriching physically engaging day spent discovering hidden gems nestled heart nature.

Begin your day with an early flight from El Calafate to Mendoza, which takes approximately 3 hours. Upon arrival head straight explore A-Uco Valley renowned wine-producing region offering stunning vineyard landscapes complemented breakfast nearby cafe R-Bröd Panadería offering delightful assortment pastries coffees set tone perfect start adventurous day.

In afternoon delve deeper into local wine culture visiting A-Andeluna Cellars participating guided wine tasting tour learning about production process sampling some finest wines region paired perfectly gourmet lunch provided winery ensuring satisfying meal amidst picturesque vineyard setting enhancing overall experience further immersing oneself unique atmosphere renowned wine-producing area.

As sun sets over scenic vineyards Mendoza take leisurely stroll through charming town center soaking tranquil atmosphere watching locals go about their evening routines providing serene backdrop concluding memorable visit historic town finally heading dinner R-1884 Restaurante Francis Mallmann celebrated traditional Argentine dishes served warm inviting environment perfect ending enriching culturally immersive day spent discovering hidden gems nestled heart country's premier wine-producing region.

Start your day with a visit to Domaine Bousquet, one of Mendoza's most renowned wineries. This family-owned vineyard is known for its organic wines and stunning views of the Andes Mountains. Begin your morning with a guided tour of the vineyard, learning about the wine-making process and sampling some of their finest offerings. For breakfast, enjoy a light meal at Ojo de Agua, which offers fresh pastries and coffee.

In the afternoon, continue your wine exploration with Buenos Aires Wine Tasting and Lunch at Bodega Gamboa. This experience includes a gourmet lunch paired with exquisite wines from the region. You'll have the opportunity to taste different varietals and learn about the unique characteristics of Mendoza's terroir. For lunch, savor a meal at Casa El Enemigo, known for its exceptional food and wine pairings.

As evening falls, take a leisurely stroll through Mendoza's charming town center, visiting local shops and cafes. Conclude your day with dinner at 1884 Restaurante Francis Mallmann, celebrated for its traditional Argentine dishes prepared using innovative techniques. The warm ambiance and delicious cuisine make it the perfect spot to end your day.

Begin your day with an early flight from Mendoza to Bariloche, which takes approximately 2 hours. Upon arrival head straight explore A-Seven Lakes Road scenic drive offering breathtaking views pristine lakes surrounded lush forests snow-capped mountains making ideal spot capturing memorable photographs complemented breakfast nearby cafe R-Mamuschka offering delightful assortment pastries coffees set tone perfect start adventurous day.

In afternoon delve deeper into natural beauty region embarking guided hiking tour Cerro Campanario providing panoramic views surrounding landscapes including Nahuel Huapi Lake Andes Mountains guides ensuring safe enjoyable experience lunch during hike enjoying packed meal prepared beforehand ensuring energy levels maintained throughout journey making most out outdoor adventure amidst breathtaking surroundings.

As sun sets over dramatic landscapes Bariloche take leisurely stroll along waterfront soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit iconic natural wonder finally heading dinner R-Alto el Fuego celebrated traditional Argentine dishes served warm inviting environment perfect ending enriching physically engaging day spent discovering hidden gems nestled heart nature.

Start your final day with a scenic drive from Bariloche to San Martin de los Andes taking approximately 3 hours passing through picturesque countryside landscapes arriving around mid-morning ready explore charming town nestled shores Lake Lacar starting off visiting A-Lanin Volcano breathtaking natural wonder offering stunning views surrounding area complemented breakfast nearby cafe R-La Costa del Pueblo offering delightful assortment pastries coffees set tone perfect start relaxing day.

In afternoon continue relaxation visiting local spa indulging rejuvenating treatments massages ensuring complete unwind after days filled adventure exploration lunch enjoying meal R-El Regional highly-rated restaurant known delicious regional cuisine served amidst cozy inviting ambiance enhancing overall dining experience further immersing oneself unique atmosphere tranquil mountain town.

As sun sets over scenic landscapes San Martin de los Andes take leisurely stroll along lakefront soaking tranquil atmosphere watching boats gently bobbing water reflecting hues twilight sky providing serene backdrop concluding memorable visit picturesque town finally heading dinner R-Kayk celebrated traditional Argentine dishes served warm inviting environment perfect ending enriching culturally immersive trip spent discovering hidden gems nestled heart nature.