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![Ultimate 5-Day Rome and Tuscany Road Trip](https://storage.googleapis.com/bd-app-dev-375714.appspot.com/itineraries/018f6459-b923-7b36-a52d-e18456eaf7c1/location343.jpg)
Ultimate 5-Day Rome and Tuscany Road Trip Itinerary
Last updated: 2024 Jun 14Iconic Rome and Pasta Delights
Morning
Start your Roman adventure with a guided tour of the Rome Colosseum, Palatine Hill and Roman Forum. After immersing yourself in ancient history, head to Pizzarium for a delicious Roman-style pizza by the slice.
Afternoon
Visit the Pantheon with a skip-the-line entry and guided tour. After marveling at this architectural wonder, indulge in a pasta making class with wine, limoncello, and cake at Rome Pasta Making Class.
Evening
Conclude your day with a fine dining experience at Ristorante Aroma, offering panoramic views of the city.
Bedtime
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![Visit Rome Colosseum, Palatine Hill and Roman Forum Guided Tour in Rome](https://cdn.getyourguide.com/img/tour/f9964a688f184da5.jpeg/21.jpg)
4.69Rome Colosseum, Palatine Hill and Roman Forum
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![Visit Rome Colosseum, Palatine Hill and Roman Forum Guided Tour in Rome](https://cdn.getyourguide.com/img/tour/f9964a688f184da5.jpeg/21.jpg)
Rome Colosseum, Palatine Hill and Roman Forum
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![Visit Pantheon in Rome](https://media.tacdn.com/media/attractions-content--1x-1/12/3f/3a/be.jpg)
4.63Pantheon
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![Visit Pantheon in Rome](https://media.tacdn.com/media/attractions-content--1x-1/12/3f/3a/be.jpg)
Pantheon
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![Visit Rome Pasta Making Class with Wine, Limoncello, and Dessert in Rome](https://cdn.getyourguide.com/img/tour/b5ca470725c80f30cb621495ce7ba265b08553af0c377d5848fafa4787330698.jpeg/21.jpg)
4.91Rome Pasta Making Class
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![Visit Rome Pasta Making Class with Wine, Limoncello, and Dessert in Rome](https://cdn.getyourguide.com/img/tour/b5ca470725c80f30cb621495ce7ba265b08553af0c377d5848fafa4787330698.jpeg/21.jpg)
Rome Pasta Making Class
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Vatican Wonders and Culinary Delights
Morning
Explore the Vatican Museums, Sistine Chapel, and St. Peter's Basilica with a guided tour. Witness the masterpieces of the Renaissance and the grandeur of St. Peter's.
Afternoon
Enjoy a pasta and tiramisu class with fine wine near the Vatican at Rome Pasta & Tiramisu Class. Learn the secrets of Italian cuisine in a fun and interactive environment.
Evening
For dinner, savor the flavors of Rome at Da Enzo Al 29, known for its authentic Roman dishes.
Bedtime
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![Visit Rome Vatican Museums, Sistine Chapel, and St. Peter's Tour in Rome](https://cdn.getyourguide.com/img/tour/63aca7c737aee.jpeg/21.jpg)
4.32Vatican Museums, Sistine Chapel, and St. Peter's Basilica
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![Visit Rome Vatican Museums, Sistine Chapel, and St. Peter's Tour in Rome](https://cdn.getyourguide.com/img/tour/63aca7c737aee.jpeg/21.jpg)
Vatican Museums, Sistine Chapel, and St. Peter's Basilica
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![Visit Rome Pasta & Tiramisu Class with Fine Wine by the Vatican in Rome](https://cdn.getyourguide.com/img/tour/641d9db8ece83.jpeg/21.jpg)
4.91Rome Pasta & Tiramisu Class
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![Visit Rome Pasta & Tiramisu Class with Fine Wine by the Vatican in Rome](https://cdn.getyourguide.com/img/tour/641d9db8ece83.jpeg/21.jpg)
Rome Pasta & Tiramisu Class
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Day Trip to the Amalfi Coast
Morning
Embark on a day trip to the Amalfi Coast with a coastal cruise, visiting Positano and enjoying the stunning views of the Mediterranean.
Afternoon
Explore the charming coastal town of Positano and savor a leisurely seafood lunch by the sea.
Borghese Gallery and Hidden Gems
Morning
Begin your day with a guided tour of the Rome Borghese Gallery, home to a remarkable collection of art and sculptures.
Afternoon
Discover the hidden gem of Trastevere, known for its picturesque streets and authentic Roman atmosphere. Enjoy a leisurely lunch at a local trattoria.
Evening
In the evening, have a fine dining experience at Il Pagliaccio, a two-Michelin-starred restaurant offering innovative cuisine.
Bedtime
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![Visit Borghese Gallery (Galleria Borghese) in Rome](https://media.tacdn.com/media/attractions-content--1x-1/12/33/95/b8.jpg)
4.42Rome Borghese Gallery
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![Visit Borghese Gallery (Galleria Borghese) in Rome](https://media.tacdn.com/media/attractions-content--1x-1/12/33/95/b8.jpg)
Rome Borghese Gallery
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Scenic Drive to Siena
Morning
Pick up your car and embark on a scenic road trip from Rome to Siena through the beautiful landscapes of Tuscany. Enjoy the freedom of the open road and make stops at charming towns along the way.
Afternoon
Arrive in Siena and check into your accommodation. Spend the afternoon exploring this medieval city, known for its stunning cathedral and historic center.
Evening
For dinner, delight your taste buds at La Pergola, a three-Michelin-starred restaurant in Rome, before continuing your journey through Tuscany the next day.
Bedtime
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