Ultimate 5-Day Rome Itinerary for History, Food, and Culture Itinerary

Enjoy a delicious breakfast at Pizzarium, a renowned spot for gourmet pizza. Then, kick off your day with a Vatican Museums (Musei Vaticani) exploration, including the breathtaking Sistine Chapel (Cappella Sistina) and the spiritual grandeur of St. Peter's Basilica (Basilica di San Pietro) with a Vatican Museums & Sistine Chapel Entrance Ticket.

For lunch, indulge in the Michelin-starred cuisine at Ristorante Aroma, offering panoramic views of the historic center. Afterward, take a leisurely stroll in the beautiful St. Peter's Square (Piazza San Pietro) and absorb the grandeur of the Vatican.

Dine at the elegant La Pergola, Rome's only three-Michelin-star restaurant, nestled in a stunning location with unparalleled views. Enjoy an exquisite dinner to cap off a day of opulence and cultural enrichment.

Start your day with a visit to the Borghese Gallery (Galleria Borghese), home to a vast collection of sculptures, paintings, and antiquities. Enhance your experience with an optional audio guide. Fuel up for the morning at Roscioli with their famous fresh bread and a selection of fine cheeses.

After the museum, take a leisurely walk to the serene Villa Borghese Park (Parco Villa Borghese), where you can rent a rowboat or simply relax amidst the lush greenery. For lunch, enjoy the ambiance and delectable dishes at Il Pagliaccio, a two-Michelin-star restaurant known for its innovative Italian cuisine.

As the sun sets, explore the quaint streets of the Trastevere district, known for its charm and vibrant nightlife. Discover hidden churches, browse artisan shops, and savor a traditional Roman dinner at Da Enzo al 29.

Embark on an unforgettable day trip from Rome to the ancient city of Pompeii and the stunning Amalfi Coast with the From Rome Pompeii, Amalfi Coast and Positano Day Trip. Explore the remarkably preserved ruins of Pompeii and then soak in the breathtaking views of the Amalfi Coast.

Enjoy a leisurely lunch in the picturesque town of Positano, overlooking the azure waters of the Mediterranean. Savor fresh seafood and local specialties at a charming coastal restaurant.

Return to Rome and unwind with a delightful dinner at Roscioli. Reflect on the day's adventures as you enjoy a selection of fine wines and sumptuous Italian dishes in the heart of the Eternal City.

Begin your final day in Rome with a visit to the majestic Pantheon, an architectural marvel of ancient Rome. Skip the line with a Rome Pantheon Skip-the-Line Ticket and marvel at the grandeur of the best-preserved monument of Roman antiquity.

For lunch, enjoy the casual elegance and delectable pastas at Trattoria Da Cesare al Casaletto. Afterward, take a leisurely walk to the historic Piazza Navona, known for its stunning fountains and Baroque architecture.

Conclude your Roman holiday with a visit to the iconic Rome Colosseum at dusk, followed by a sumptuous farewell dinner at Il Pagliaccio, where you'll be treated to an unforgettable dining experience with innovative flavors and impeccable service.