Ultimate 5-Day Rome Itinerary with Vatican and Colosseum Highlights Itinerary

Indulge in a delightful breakfast at La Pergola, the only three-Michelin-star restaurant in Rome. Then, skip the line and explore the renowned Vatican Museums (Musei Vaticani) with the extraordinary Sistine Chapel (Cappella Sistina) on a guided tour, followed by a visit to the magnificent St. Peter's Basilica (Basilica di San Pietro).

For lunch, enjoy the innovative pizzas at Pizzarium, a favorite spot among locals. Afterward, take a leisurely walk to the nearby St. Peter's Square (Piazza San Pietro), soaking in the grandeur of the Vatican.

Relax with a guided food tour in the charming neighborhood of Trastevere, tasting a variety of Roman delicacies and wines. Explore the cobblestone streets and vibrant piazzas, immersing yourself in the local culture and culinary scene.

Start your day with a visit to the lush Villa Borghese Gardens (Giardino di Villa Borghese), where you can enjoy a peaceful morning stroll. Grab a quick bite at the garden's cafe or visit Caffè Sant'Eustachio for their famous coffee before heading to the nearby Borghese Gallery (Galleria Borghese) for a guided tour of its exquisite art collection.

After the gallery, have a leisurely lunch at Antico Arco, known for its innovative Roman cuisine. Spend your afternoon exploring the stunning Pantheon and the picturesque Piazza Navona, admiring the Baroque architecture and fountains.

Dine at Il Pagliaccio, a two-Michelin-star restaurant, for an unforgettable gastronomic experience. Afterward, take a romantic evening stroll to the Spanish Steps (Piazza di Spagna) and enjoy the charming atmosphere.

Enjoy a relaxed morning with breakfast at Trattoria Da Cesare al Casaletto, known for its authentic Roman dishes. Savor the flavors before embarking on a self-guided exploration of the lesser-known sites of Rome, such as the Circus Maximus (Circo Massimo) and the Arch of Constantine (Arco di Costantino).

For lunch, visit La Gatta Mangiona and indulge in their delectable pizzas and other specialties. Afterward, take a guided tour of the Catacombs of Rome (Catacombe di Roma), delving into the underground burial chambers and learning about ancient Roman burial practices.

Experience the vibrant nightlife of Rome in the Monti district, known for its eclectic mix of bars and boutiques. Enjoy a casual dinner at Antico Forno Roscioli, famous for its traditional Roman pizzas and baked goods.

Begin your last day with breakfast at Trapizzino Testaccio, where you can try the innovative "trapizzino," a cross between a pizza and a sandwich. After breakfast, visit the Trevi Fountain (Fontana di Trevi) to witness its magnificence in the morning light and participate in the tradition of tossing a coin into the fountain.

Enjoy a sumptuous lunch at Hostaria Da Enzo, known for its authentic Roman cuisine. Then, take a guided tour of the Rome Colosseum, Palatine Hill and Roman Forum, immersing yourself in the history of ancient Rome.

For your final dinner in Rome, indulge in the innovative dishes at Per Me Ristorante. Afterward, take a leisurely stroll through the charming Trastevere, enjoying the lively atmosphere and street performances.