Ultimate 5-Day Rome Itinerary with Vatican and Colosseum Highlights Itinerary

Enjoy a delightful breakfast at Pizzarium, a renowned spot for mouthwatering Roman-style pizza. Fuel up for a morning of exploration that begins with a Vatican Museums (Musei Vaticani) tour, including access to the iconic Sistine Chapel (Cappella Sistina).

For lunch, indulge in the Michelin-starred cuisine at Ristorante Aroma, offering panoramic views of the city. Afterward, visit the spiritual haven of St. Peter's Basilica (Basilica di San Pietro) and bask in the architectural magnificence.

As the day winds down, take a leisurely walk to St. Peter's Square (Piazza San Pietro) and witness the stunning colonnades. For dinner, experience the elegant ambiance and exquisite dishes at La Pergola, the only three-Michelin-star restaurant in Rome.

Start with a classic Roman breakfast at Roscioli, known for its fresh pastries and artisanal coffee. Energized, head to the Pantheon, one of the best-preserved ancient Roman buildings, and marvel at its architectural perfection.

Enjoy a leisurely lunch at Il Pagliaccio, a two-Michelin-star restaurant offering innovative Italian cuisine. Afterward, immerse yourself in the masterpieces of the Borghese Gallery (Galleria Borghese) with a guided tour, and stroll through the tranquil Borghese Gardens.

For dinner, indulge in the creative dishes at Roscioli itself, which transforms into a cozy and atmospheric restaurant in the evening. Conclude your day with a romantic walk along the Ponte Sant'Angelo, taking in the breathtaking views of the Tiber River and the city's skyline.

Embark on a morning adventure with a visit to the Rome Guided Roman Catacombs Tour with Transfers. Explore the underground burial chambers and learn about early Christian history. Afterward, enjoy a light-hearted breakfast at Pizzarium, known for its delectable pizza by the slice.

For lunch, savor the flavors of Rome at Da Enzo al 29, where the menu is filled with traditional dishes. Spend your afternoon visiting the impressive Castel Sant’Angelo (Mausoleum of Hadrian) with a skip-the-line ticket and audio guide, and enjoy panoramic views of the city from the terrace.

Dine at Roscioli, a celebrated restaurant offering a selection of exquisite dishes. Cap off your evening with a visit to the charming Piazza Navona, where you can admire Bernini's Fountain of the Four Rivers and soak in the lively atmosphere.

Begin your final day with a visit to the Rome Colosseum, where you'll participate in a Rome Colosseum Tour with Access to the Gladiator Arena. Immerse yourself in the history of this iconic amphitheater. For breakfast, enjoy the artisanal delights at Roscioli, a local favorite.

After exploring the Colosseum, enjoy a sumptuous lunch at Trattoria Da Cesare al Casaletto, known for its authentic Roman cuisine. Spend your afternoon wandering through the ruins of the Roman Forum (Foro Romano) and the majestic Palatine Hill (Palatino), where ancient emperors once walked.

As the sun sets on your Roman holiday, indulge in a farewell dinner at La Pergola, the only three-Michelin-star restaurant in Rome, offering unparalleled culinary experiences. End your trip with a romantic visit to the Trevi Fountain (Fontana di Trevi), where you can partake in the tradition of tossing a coin to ensure your return to the Eternal City.