5-day trip to Rome: Exploring Ancient History and Vatican City Itinerary

Start your day with a guided tour of the Vatican Museums (Musei Vaticani) and the Sistine Chapel (Cappella Sistina). Marvel at the stunning art and architecture, including Michelangelo's famous frescoes. Afterward, visit the magnificent St. Peter's Basilica (Basilica di San Pietro).

Enjoy a leisurely lunch at Pizzarium, known for its delicious pizza slices. Afterward, take a hop-on hop-off bus tour with Rome City Sightseeing Hop-on Hop-off Bus with Audioguide to explore other attractions in Rome, such as Pantheon and Piazza Navona.

Indulge in a fine dining experience at La Pergola, a Michelin-starred restaurant offering panoramic views of Rome. After dinner, take a romantic evening walk around Trastevere and enjoy the charming atmosphere of this historic neighborhood.

Start your day with a guided tour of the Raphael's Rooms (Stanze di Raffaello) within the Vatican Museums. Admire the beautiful frescoes painted by Raphael. Afterward, visit the Castel Sant'Angelo National Museum (Museo Nazionale di Castel Sant'Angelo) and enjoy panoramic views of Rome from the top.

Enjoy a delightful lunch at Trattoria Da Cesare al Casaletto, known for its traditional Roman dishes. Afterward, explore the Rome Jewish Ghetto (Ghetto Ebraico di Roma) and learn about the rich Jewish history of Rome. Visit the Campo de' Fiori market for some local shopping.

Have dinner at Il Pagliaccio, a Michelin-starred restaurant offering innovative Italian cuisine. Afterward, take a relaxing evening stroll to Piazza del Campidoglio and enjoy the beautiful view of the Roman Forum.

Start your day with a visit to the Borghese Gallery (Galleria Borghese). Explore the impressive collection of art, including works by Bernini and Caravaggio. Afterward, take a walk through the Villa Borghese Gardens and enjoy the peaceful surroundings.

Enjoy a delicious lunch at Ristorante Aroma, located on the rooftop of the Palazzo Manfredi. Afterward, visit the Pantheon and take a guided tour to learn about its fascinating history and architecture.

Have dinner at Ristorante Aroma and savor the panoramic views of the city. Afterward, visit the Piazza del Popolo and take a leisurely walk along the Spanish Steps (Piazza di Spagna).

Take a high-speed train from Rome to Florence and explore the beautiful city known for its Renaissance art and architecture. Visit the Duomo (Cattedrale di Santa Maria del Fiore) and climb to the top for a breathtaking view of Florence.

Enjoy a traditional Tuscan lunch at Trattoria Mario. Afterward, visit the Uffizi Gallery (Galleria degli Uffizi) to admire masterpieces by Botticelli, Michelangelo, and Leonardo da Vinci.

Take a leisurely walk along the Ponte Vecchio and enjoy the romantic atmosphere of the Arno River. Have dinner at Trattoria Sostanza and savor authentic Florentine cuisine. Return to Rome in the evening.