Ultimate 5-Day Rome Itinerary with Vatican, Colosseum, and More Itinerary

Kick off the day with a delightful breakfast at La Pergola, offering stunning views and a sumptuous spread. Then, head to the spiritual heart of the Vatican and enjoy the renowned Rome Vatican Museums, Sistine Chapel & St. Peter's Basilica Tour. Marvel at the masterpieces in the Vatican Museums (Musei Vaticani), stand in awe of the Sistine Chapel (Cappella Sistina), and explore the sacred St. Peter's Basilica (Basilica di San Pietro) with a knowledgeable guide.

For lunch, indulge in gourmet pizza at Pizzarium, a favorite spot among locals and visitors alike. Afterward, take a leisurely stroll through the charming streets of Vatican City (Citta del Vaticano), perhaps visiting the St. Peter's Square (Piazza San Pietro) again for a different perspective.

Enjoy a relaxing evening with a visit to the lush Villa Borghese Park (Parco Villa Borghese). Take in the serene atmosphere and beautiful views. For dinner, experience the innovative flavors of Il Pagliaccio, a two-Michelin-star restaurant known for its exquisite cuisine and elegant ambiance.

Start early with a grab-and-go breakfast at Trattoria Da Cesare al Casaletto, preparing you for a day of exploration. Embark on an unforgettable From Rome Tuscany Guided Day Trip with Lunch & Wine Tasting. Delight in the rolling vineyards, charming villages, and world-class wines of the Tuscan region. Savor a traditional Tuscan lunch and wine tasting, immersing yourself in the flavors of Italy.

Upon returning to Rome, take some time to relax and enjoy a casual afternoon coffee at Caffè Sant'Eustachio, known for its exceptional brew. You can also explore the quaint neighborhood around the Pantheon and enjoy the stunning architecture and lively atmosphere.

For dinner, indulge in the delectable dishes at Salumeria Roscioli, where the menu is a celebration of Italian flavors. Afterward, take an evening stroll to the Piazza Navona and witness the lively street performers and the grandeur of the fountains under the Roman moonlight.

Begin your day with the perfect espresso and a light breakfast at Antico Caffè Greco, the oldest bar in Rome. Energized, set off to explore the iconic Pantheon and the well-preserved Catacombs of Rome (Catacombe di Roma). Gain insight into ancient Roman and Christian history with guided tours of these fascinating sites.

For lunch, enjoy the warm and welcoming atmosphere of Hostaria Costanza, serving classic Roman dishes. Afterward, take a leisurely walk through the picturesque Trastevere, known for its narrow cobblestone streets and authentic Roman feel.

As the sun sets, indulge in a gourmet dining experience at All'Oro, where the chef's innovative take on traditional Italian dishes will tantalize your taste buds. Cap off the night with a visit to the Rome Civitavecchia Cruise Port (Civitavecchia Terminal Crociere), enjoying the sea breeze and reflecting on the wonders of your Roman journey.

Savor a delightful breakfast at Pane e Salame, a local favorite known for its fresh bread and cured meats. Afterward, embark on a journey through the vibrant history of Rome with the Rome City Sightseeing Hop-on Hop-off Bus with Audioguide. Visit the city's renowned landmarks at your own pace, hopping on and off as you please.

For lunch, enjoy the laid-back atmosphere and delicious Roman-Jewish cuisine at Beppe e I Suoi Formaggi. Spend your final afternoon exploring the hidden gems of Rome or visiting any must-see sites you haven't had the chance to experience yet.

Conclude your Roman journey with a memorable dinner at Matricianella, savoring the flavors of traditional Roman dishes. After dinner, take a leisurely walk to the Spanish Steps (Piazza di Spagna) and enjoy the beautiful surroundings, reflecting on the incredible memories you've made during your time in the Eternal City.