Ultimate 22-Day Italy Adventure: Rome, Naples, Sorrento, Amalfi Coast, Sicily, Pompeii, Florence, Siena, Lake Como, Portofino, Venice Itinerary

Kick off your day with a delightful breakfast at La Pergola, offering a luxurious setting and a sumptuous menu. Post breakfast, head to the awe-inspiring Vatican Museums (Musei Vaticani) and explore the world-renowned art collections. Don't miss the chance to witness the breathtaking Sistine Chapel (Cappella Sistina).

For lunch, enjoy a gastronomic experience at St. Peter's Basilica (Basilica di San Pietro), which offers a selection of fine Italian dishes. After lunch, visit the magnificent St. Peter's Basilica (Basilica di San Pietro) and marvel at its grandeur. Climb to the top for a panoramic view of the Vatican City and Rome.

Conclude your Vatican tour with a visit to St. Peter's Square (Piazza San Pietro) and bask in the glory of the monumental square. For dinner, head to Pizzarium for some of the best pizza in Rome, a perfect way to end your day.

Start your day with a visit to the iconic Colosseum (Colosseo). Explore this ancient amphitheater with a skip-the-line guided tour and immerse yourself in the history of gladiator battles and Roman entertainment. Nearby, the Arch of Constantine (Arco di Costantino) awaits for a photo opportunity.

After working up an appetite, enjoy a traditional Roman lunch at Roman Forum (Foro Romano), where you can dine with a view of the ancient ruins. Post-lunch, visit the Palatine Hill (Palatino) and explore the lush landscape and the ruins of the imperial palaces.

For a memorable evening, join a guided golf cart tour Rome Guided Golf Cart 3-Hour Tour to discover the hidden gems of Rome. Conclude your day with a delightful dinner at Trattoria Da Cesare al Casaletto, known for its authentic Roman dishes and warm hospitality.

Begin your day with a visit to the serene Borghese Gallery (Galleria Borghese). Explore the exquisite collection of art and sculptures in one of Rome's most beautiful villas. Advance reservations are recommended.

After soaking in the artistic masterpieces, take a leisurely walk through the picturesque gardens of Villa Borghese. Enjoy the greenery and perhaps indulge in a casual lunch at one of the charming cafes within the park.

As the sun sets, head to the trendy neighborhood of Trastevere. Explore the narrow cobblestone streets and vibrant piazzas. For dinner, try the authentic Roman cuisine at Da Enzo al 29, a local favorite known for its traditional dishes and cozy atmosphere.

Embark on a unique culinary journey with a Rome Make Your Own Fettuccine and Tiramisù Cooking Class. Learn the secrets of Italian pasta and dessert making from a local chef. Enjoy the fruits of your labor for lunch.

Post-lunch, visit the lesser-known but equally fascinating Catacombs of Rome (Catacombe di Roma). Explore the underground burial chambers and learn about the early Christian history of Rome.

For a memorable final evening in Rome, dine at Il Pagliaccio, a Michelin-starred restaurant offering innovative and refined Italian cuisine. After dinner, take a leisurely stroll through the city, savoring the unforgettable moments and the timeless beauty of Rome's streets and monuments.

Begin your day with a traditional Neapolitan breakfast at Bar Nilo, where you can enjoy a caffè espresso and a sfogliatella, a local pastry. After breakfast, take a walk to the Naples National Archaeological Museum (Museo Archeologico Nazionale di Napoli) to explore one of the most important archaeological museums in the world, housing a vast collection of Roman artifacts from nearby Pompeii and Herculaneum.

For lunch, savor the flavors of Naples at Pizzeria Brandi, the place where the famous pizza Margherita was invented. After lunch, take a stroll through the historic center of Naples, a UNESCO World Heritage site, and visit the impressive Naples Cathedral (Duomo) and the Church of Gesù Nuovo (Chiesa di Gesù Nuovo) with its unique facade.

Enjoy a delightful dinner at Trattoria da Nennella, a cozy trattoria serving authentic Neapolitan dishes. After dinner, take a leisurely walk along the Naples Promenade (Lungomare) and enjoy the stunning views of the Bay of Naples and the majestic Mount Vesuvius.

Start your day with a refreshing breakfast at Bar Syrenuse, where you can enjoy a fresh glass of orange juice made from the famous Sorrento oranges. After breakfast, take a walk to the Vallone dei Mulini, a hidden valley with abandoned mills, and the Sedile Dominova, a historic seat where the nobles of Sorrento used to meet.

For lunch, head to Ristorante Tasso, named after the famous Sorrentine poet, and enjoy a meal with a view of the bustling Piazza Tasso. After lunch, visit the Chiesa di San Francesco, a beautiful church with a quiet cloister, and the Museo Correale, which houses a rich collection of art and decorative arts.

Indulge in a luxurious dinner at Don Alfonso 1890, a two-Michelin-star restaurant known for its innovative cuisine and extensive wine list. After dinner, take a romantic walk through the Sorrento Peninsula and enjoy the breathtaking views of the Amalfi Coast and the shimmering waters of the Tyrrhenian Sea.

Embark on a picturesque drive along the Amalfi Drive (Strada Statale 163), one of the most scenic coastal roads in the world. Stop at Positano and explore the charming village with its colorful buildings and narrow streets. Visit the Chiesa di Santa Maria Assunta with its iconic dome and the Positano Spiaggia, the main beach of Positano.

For lunch, enjoy the stunning views and fresh seafood at Amalfi, the largest town on the coast. After lunch, visit the Duomo di Sant'Andrea (Cattedrale di Sant'Andrea), a 9th-century cathedral with a mesmerizing facade, and the Museo della Carta, a paper museum showcasing the traditional craft of papermaking in Amalfi.

As the sun sets, head to Ristorante Marina Grande 1925 in Sorrento Peninsula for a romantic dinner by the sea. Savor the flavors of the Amalfi Coast and raise a glass of Limoncello, the famous local liqueur, to a day well spent.

Begin your Sicilian adventure with a traditional breakfast at Bar Turrisi in Castelmola, a charming hilltop village. Sip on a cappuccino and savor a freshly baked cornetto while enjoying panoramic views of the surrounding landscape.

After breakfast, visit the ancient Theatre of Taormina (Teatro Antico di Taormina) and immerse yourself in the rich history of the region. For lunch, indulge in Sicilian delicacies at Ristorante La Griglia in Taormina, known for its fresh seafood and traditional flavors.

Explore the beautiful Taormina and its narrow streets lined with boutique shops and historic buildings. For dinner, enjoy a fine dining experience at Ristorante Gambero Rosso and sample exquisite dishes paired with local wines. End your day with a leisurely stroll along the Taormina Coast (Riviera di Taormina) and take in the stunning views of the Mediterranean.

Start your day with a visit to the ancient Ancient Theatre of Syracuse (Teatro Greco), where you can explore the fascinating ruins of an ancient Greek theater. Afterward, enjoy a traditional Sicilian breakfast at Bar Savoia in Syracuse, known for its excellent coffee and pastries.

After breakfast, head to the majestic Mount Etna (Mongibello), Europe's highest and most active volcano. Take a guided tour of the volcano and its surroundings, and if you're feeling adventurous, you can even hike to the summit. For lunch, enjoy a meal with a view at Ristorante Al Saraceno in Taormina, offering panoramic vistas of the coast and the surrounding landscape.

Conclude your day with a visit to the Ortygia island, the historical heart of Syracuse. Explore the charming streets and visit the Temple of Apollo (Tempio di Apollo), one of the most important ancient Greek monuments in Sicily. For dinner, try the innovative Sicilian cuisine at Restaurant Don Camillo, and savor the unique flavors of the island.

Begin your day with a visit to the stunning Noto, a UNESCO World Heritage-listed town known for its exquisite Baroque architecture. Explore the elegant palaces, churches, and the grand cathedral. For breakfast, enjoy the local specialties at Barocco Caffè, a charming cafe in the heart of Noto.

After soaking in the Baroque splendor, head to the Vendicari Nature Reserve (Riserva Naturale di Vendicari) for a leisurely afternoon. Explore the diverse ecosystems, spot migratory birds, and relax on the pristine beaches. For lunch, pack a picnic or visit La Corte del Sole for a delightful meal with a view of the surrounding countryside.

As the sun sets, return to Noto and explore the vibrant Corso Vittorio Emanuele, the main street lined with boutiques, cafes, and gelaterias. For dinner, indulge in the Sicilian flavors at Ristorante Manna, and savor the fresh local produce and seafood. End your day with a stroll through the town under the soft glow of the streetlights.

Start your day with a visit to the Egadi Islands (Isole Egadi), a stunning archipelago off the western coast of Sicily. Take a boat tour to explore the crystal-clear waters, hidden coves, and the charming island villages. For breakfast, enjoy the fresh sea breeze and the panoramic views on board.

For lunch, visit the picturesque Marettimo, the westernmost and most wild of the Egadi Islands. Enjoy a meal of freshly caught fish and seafood at Ristorante Il Veliero, with a view of the harbor and the azure waters. After lunch, take a walk to explore the island's rugged coastline and the Mediterranean scrubland.

Return to the main island of Sicily and enjoy a relaxed evening in Trapani. Explore the historic center, visit the Cattedrale di San Lorenzo (Duomo di Trapani), and stroll along the Corso Vittorio Emanuele with its boutiques and cafes. For dinner, try the local specialties at Ristorante La Bettolaccia, and end your day with a glass of the region's famous Marsala wine.

Begin your day with a visit to the Archipelago of the Aeolian Islands (Isole Eolie), a UNESCO World Heritage site known for its volcanic landscapes and cultural significance. Explore the islands by boat, visiting the active volcano of Stromboli and the stunningly beautiful Panarea.

For lunch, enjoy the fresh catch of the day at Ristorante Il Cappero on the island of Salina, known for its delicious seafood and panoramic views. After lunch, take a walk through the charming village and visit the Museo Archeologico Regionale Eoliano (Baglio Capo Graziano) to learn about the history and archaeology of the Aeolian Islands.

Return to the main island of Sicily and enjoy a relaxed evening in Milazzo. Explore the historic center, visit the Castello di Milazzo, and stroll along the Corso Umberto I with its boutiques and