Ultimate 5-Day Rome Itinerary with Top Attractions and Dining Itinerary

Kick off the morning with a visit to the spiritual heart of the Vatican at St. Peter's Basilica (Basilica di San Pietro). Marvel at its stunning architecture and the works of Michelangelo. For a quick bite, grab a pastry at Pizzarium, known for its gourmet pizza by the slice.

Enjoy a guided tour of the Vatican Museums (Musei Vaticani) and the Sistine Chapel (Cappella Sistina) with the Rome Vatican Museums, Sistine Chapel, and Basilica Tour. Witness the breathtaking masterpieces and the famous ceiling painted by Michelangelo.

For a more relaxed evening, take a stroll in the charming neighborhood of Trastevere. Dine at Trattoria Da Cesare al Casaletto, known for its traditional Roman dishes and warm hospitality.

Embark on a day trip to the picturesque region of Tuscany. Enjoy a guided tour with the From Rome Tuscany Guided Day Trip with Lunch & Wine Tasting. Explore the rolling hills, vineyards, and medieval villages while sampling the renowned wines and savoring a Tuscan lunch.

Return to Rome and take a leisurely walk to the Spanish Steps (Piazza di Spagna). Climb the steps and admire the elegant surroundings. For a sweet treat, indulge in the famous tiramisu at Il Pagliaccio.

Experience the romance of the Eternal City with an evening Rome Fast-Track Colosseum and Forum Ticket with Audio Guide. Relive the glory of ancient Rome as you explore the illuminated Colosseum and the ancient ruins.

Start off with a visit to the serene Borghese Gallery (Galleria Borghese). Explore the exquisite collection of art and take a stroll in the beautiful Borghese Gardens. For a quick bite, enjoy a light lunch at La Pergola, known for its elegant setting and gourmet cuisine.

Discover the hidden gem of Campo de' Fiori, a vibrant market square surrounded by cafes and historic buildings. Immerse yourself in the lively atmosphere and then visit the ancient Catacombs of Rome (Catacombe di Roma) to explore the underground burial chambers.

Dine at La Pergola, one of Rome's most prestigious restaurants, and indulge in a Michelin-starred dining experience. Savor the innovative dishes and fine wines in an elegant and romantic setting.

Begin your final day with a cinematic experience at the Cinecittà Studios (Studios di Cinecittà), the legendary home of Italian cinema. Explore the sets and exhibitions that bring the magic of film to life. For breakfast, enjoy the ambiance and pastries at Roscioli, a true Roman institution.

Spend your afternoon exploring the ancient Appian Way (Via Appia Antica) , one of the most important and strategic Roman roads of its time. Rent a bike or take a guided tour and visit the impressive ruins and catacombs along the way. For a refreshing break, stop for a snack at Ercoli 1928, a historic deli offering a variety of gourmet treats.

As you prepare to depart, take in the final views of Rome at the Janiculum Hill (Gianicolo). This panoramic spot offers a stunning vista of the city and is the perfect place to reflect on your Roman adventure. For a farewell dinner, enjoy the innovative Roman-Jewish cuisine at Sora Lella, a restaurant with a rich history and a menu to match.