Ultimate 5-Day Rome Itinerary with Vatican and Colosseum Highlights Itinerary

Fuel up for the day with a cappuccino and a pastry at Pizzarium, a favorite spot for pizza lovers. Then, skip the line and immerse yourself in the Vatican Museums (Musei Vaticani) with the Vatican Museums & Sistine Chapel Entrance Ticket. Spend your morning admiring world-renowned art collections.

Take a break for lunch at La Pergola, the only 3-Michelin-star restaurant in Rome, known for its exquisite cuisine. Afterward, explore the sacred Sistine Chapel (Cappella Sistina) and the spiritual grandeur of St. Peter's Basilica (Basilica di San Pietro) with a guided tour or an audio guide.

Enjoy a relaxed evening at St. Peter's Square (Piazza San Pietro), taking in the grandeur of the architecture. For dinner, try Trattoria Da Cesare al Casaletto, a local favorite known for its Roman specialties and warm hospitality.

Start your day with a guided food tour in the charming neighborhood of Trastevere with the Rome Guided Food Tour in Trastevere. Sample a variety of local delicacies and learn about the culinary traditions of Rome.

After a delightful food tour, take a leisurely stroll to the Pantheon, one of the best-preserved ancient Roman buildings. Explore the majestic interior and learn about its fascinating history. For lunch, enjoy the innovative Roman cuisine at Il Pagliaccio, a 2-Michelin-star restaurant.

Spend a relaxing evening at the beautiful Piazza Navona, known for its stunning fountains and Baroque architecture. Dine at Ristorante Aroma, where you can enjoy a sophisticated meal with a view of the historic city center.

Take a leisurely morning to enjoy a hearty breakfast at Roscioli, known for its artisanal breads and pastries. Then, visit the elegant Spanish Steps (Piazza di Spagna) and the nearby upscale boutiques for a morning of shopping and leisurely strolls.

For lunch, indulge in the delectable sandwiches and paninis at Roscioli, a local favorite. Afterward, visit the Borghese Gallery (Galleria Borghese) to admire its impressive collection of art and sculptures. It's recommended to book tickets in advance.

As the day winds down, enjoy a delightful dinner at Da Enzo Al 29, known for its cozy atmosphere and traditional Roman dishes. Cap off the evening with a visit to the Rome Civitavecchia Cruise Port (Civitavecchia Terminal Crociere) to watch the sunset over the Mediterranean.

Begin your final day with a visit to the Circus Maximus (Circo Massimo), where ancient chariot races once took place. Enjoy a morning coffee and pastry at Pizzarium, located nearby.

Explore the fascinating Catacombs of Rome (Catacombe di Roma), where early Christians buried their dead and practiced their faith in secret. For lunch, savor the flavors of Rome at Trattoria Da Cesare al Casaletto, known for its authentic Roman cuisine.

Reflect on your trip with a visit to the Arch of Constantine (Arco di Costantino), a triumphal arch celebrating a famous Roman victory. Enjoy a farewell dinner at Il Pagliaccio, a 2-Michelin-star restaurant that offers innovative dishes in an elegant setting.